Human BIRC5 / Survivin

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Human recombinant protein (aa M1-D142).

Human BIRC5 / Survivin

• IHC
• IHC - Paraffin (0.5 - 1 µg/ml)
• Western blot (0.5 - 1 µg/ml)
• ELISA (0.1 - 0.5 µg/ml)

Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. It is a member of the inhibitor of apoptosis (IAP) family. The gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and two-color FISH. The Survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. It is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

Lyophilized from PBS, 0.025% sodium azide.

Reconstitute in sterile distilled water.

Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: O15392 NCBI: NM_001168 NP_001159.2