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BCL7B is a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.
Gene Name: | B-Cell CLL/Lymphoma 7B |
Family/Subfamily: | Cancer |
Synonyms: | BCL7B, Allergen Hom s 3, B-cell CLL/lymphoma 7B |
Target Sequences: | NM_001707 NP_001698.2 Q9BQE9 |
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