Recombinant Monoclonal Rabbit anti‑Human BCL10 / BCL‑10 Antibody (clone BL10/2988R, Azide‑free,Carrier‑free, aa122‑168, IHC, IF) LS‑C751432
Recombinant Monoclonal Rabbit anti‑Human BCL10 / BCL‑10 Antibody (clone BL10/2988R, Azide‑free,Carrier‑free, aa122‑168, IHC, IF) LS‑C751432
Antibody:
BCL10 / BCL-10 Rabbit anti-Human Recombinant Monoclonal (aa122-168) (Azide-free, Carrier-free) (BL10/2988R) Antibody
Application:
IHC-P, IF, Flo
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
BCL10 / BCL-10 Rabbit anti-Human Recombinant Monoclonal (aa122-168) (Azide-free, Carrier-free) (BL10/2988R) Antibody
Application:
IHC-P, IF, Flo
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
BCL-10 antibody LS-C751432 is an unconjugated rabbit recombinant monoclonal antibody to human BCL-10 (BCL10) (aa122-168). Validated for Flow, IF and IHC.
Target
Human BCL10 / BCL-10
Synonyms
BCL10 | Bcl-10 | B-cell CLL/lymphoma 10 | B-cell lymphoma/leukemia 10 | CARMEN | CARD-like apoptotic protein | CCARMEN | C-E10 | CIPER | Cellular-E10 | HCLAP | Cellular homolog of vCARMEN | CLAP | ME10
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
Recombinant human BCL10 protein fragment (around aa122-168). Antigen Molecular Weight: 33 kDa
Specificity
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kappa-B activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Applications
- IHC - Paraffin (0.5 - 1 µg/ml)
- Immunofluorescence (1 - 2 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
Immunohistology (Formalin-fixed - 0.5-1 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
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Human
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Applications:
IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/4/2024