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Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
Gene Name: | thyroid hormone receptor interactor 6 |
Synonyms: | TRIP6, Opa-interacting protein 1, TRIP6i2, OIP-1, OIP1, ZRP-1, Zyxin related protein 1, TR-interacting protein 6, Zyxin-related protein 1, TRIP-6 |
Target Sequences: | NP_003293.2 Q15654 |
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