Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
ZNF280B antibody was raised against synthetic peptide from N-Terminus of human ZNF280B (Q86YH2, NP_542942). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Bovine, Pig (100%); Galago (92%).
LS-E11264 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C146506. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human ZNF280B / SUHW2
Lyophilized from PBS with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
ZNF280B Antibody, 5OY11.1 Antibody, 5'OY11.1 Antibody, SUHW2 Antibody, Zinc finger protein 279 Antibody, ZNF632 Antibody, Zinc finger protein 632 Antibody, D87009.C22.3 Antibody, Zinc finger protein 280B Antibody, ZNF279 Antibody
ZNF280B is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding.