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Anti-YES1 / c-Yes Antibody IHC-plus™ LS-B4193

Note: This antibody replaces LS-C109319

Ordering

Wt. Vol. Conc. Price
- 50 µl 1 mg/ml $395

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

YES1 / c-Yes Antibody LS-B4193 Images

[click image for a larger image and more details]
Immunohistochemistry
Anti-YES1 antibody IHC of human breast.
Immunohistochemistry
Anti-YES1 antibody IHC of human placenta.
Immunofluorescence
Immunofluorescence of methanol-fixed HeLa, using c-Yes antibody at 1:200 dilution.
Western blot
Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. YES1 antibody diluted at 1:1000.
Western blot
Sample (30 ug of whole cell lysate). A: A431. 7.5% SDS PAGE. YES1 antibody diluted at 1:1000.

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Rabbit Polyclonal to Human YES1 / c-Yes
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated

Details

Human YES1 / c-Yes
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (10 µg/ml), ICC, Immunofluorescence (1:100 - 1:200), Western blot (1:500 - 1:3000)

Specificity and Use

YES1 / c-Yes antibody was raised against recombinant protein fragment containing a sequence corresponding to a region within amino acids 284 and 541 of c-Yes.
Human and mouse c-Yes. Predicted cross-reactivity based on amino acid sequence homology: rat (88%), bovine (89%), dogs (98%), zebrafish (95%).

Packaging

PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal
Aliquot and store at -20°C. Minimize freezing and thawing.
For research use only.

About YES1 / c-Yes

P07947 NM_005433 NP_005424.1

YES1 Antibody, C-yes Antibody, Cyes Antibody, Cellular yes-1 protein Antibody, HsT441 Antibody, Oncogene kinase yes1 Antibody, p61-YES Antibody, p61yes Antibody, p62c-yes Antibody, Proto-oncogene c-Yes Antibody, Tyrosine-protein kinase Yes Antibody, Yes kinase Antibody, v-yes Antibody, Yes Antibody, Yamaguchi sarcoma oncogene Antibody

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.

Immunohistochemistry

Immunohistochemistry
Anti-YES1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4193 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-YES1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4193 concentration 10 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of methanol-fixed HeLa, using c-Yes antibody at 1:200 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. YES1 antibody diluted at 1:1000.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A: A431. 7.5% SDS PAGE. YES1 antibody diluted at 1:1000.
 

Requested From: United States
Date Requested: 8/30/2015

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