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Anti-YES1 / c-Yes Antibody (aa1-30) LS-C99398

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular YES1 / c-Yes Antibodies

Anti-YES1 / c-Yes Antibody IHC-plus™ LS-B4193
Rabbit Polyclonal to Human YES1 / c-Yes
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-YES1 / c-Yes Antibody (clone 2D5) LS-C133516
Mouse Monoclonal [clone 2D5] (IgG1,k) to Human YES1 / c-Yes
Human
Western blot, ELISA
Unconjugated
Western blot Image
Anti-YES1 / c-Yes Antibody (aa1-30, Biotin) LS-C273792
Rabbit Polyclonal (IgG) to Human YES1 / c-Yes
Human
Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human YES1 / c-Yes
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Human YES1 / c-Yes
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

YES1 / c-Yes antibody was raised against kLH-conjugated synthetic peptide between amino acids 1-30 from N-terminal region of human YES1.
LS-E9225 - Lyophilized - 100 µg - $145.00
aa1-30

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About YES1 / c-Yes

P07947 NM_005433 NP_005424.1

YES1 Antibody, C-yes Antibody, Cyes Antibody, Cellular yes-1 protein Antibody, HsT441 Antibody, Oncogene kinase yes1 Antibody, p61-YES Antibody, p61yes Antibody, p62c-yes Antibody, Proto-oncogene c-Yes Antibody, Tyrosine-protein kinase Yes Antibody, Yes kinase Antibody, v-yes Antibody, Yes Antibody, Yamaguchi sarcoma oncogene Antibody

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
YES Antibody (K11) western blot of 293 cell line lysates (35 ug/lane). The YES antibody detected the YES protein (arrow).

Western blot

Western blot
Western blot of anti-YES antibody in mouse kidney tissue lysate. YES (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
 

Requested From: United States
Date Requested: 12/7/2016

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