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Anti-YES1 / c-Yes Antibody (aa1-252) LS-C40275

Catalog Size Price
LS-C40275-200 200 µg Unavailable

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41 YES1 / c-Yes Antibodies

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Immunohistochemistry of paraffin-embedded mouse brain using YES1 antibody at dilution of 1:100 (40x lens).

100% Guaranteed
Rabbit Polyclonal (IgG) to Human YES1 / c-Yes
Human, Mouse, Chicken
Western blot, Immunoprecipitation (applications tested for the base form of this product only)


Human YES1 / c-Yes
Human, Mouse, Chicken (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein A purified


  • Western blot (0.5 - 2 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

YES1 / c-Yes antibody was raised against trpE fusion protein corresponding to aa 1-252 of human Yes Kinase.
Recognizes human p62 Yes Kinase, which occasionally appears as a doublet of 59kD and 62kD. Species cross-reactivity: human, mouse and chicken.
Suitable for use in Western Blot. Not recommended for Immunoprecipitation. Western Blot: 0.5-2 ug/ml detects Yes Kinase in RIPA lysates from Jurkat cells. Jurkat cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-Yes (1 ug/ml). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.


0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide.
For research use only.

About YES1 / c-Yes

P07947 NM_005433 NP_005424.1

YES1 Antibody, C-yes Antibody, Cyes Antibody, Cellular yes-1 protein Antibody, HsT441 Antibody, Oncogene kinase yes1 Antibody, p61-YES Antibody, p61yes Antibody, p62c-yes Antibody, Proto-oncogene c-Yes Antibody, Tyrosine-protein kinase Yes Antibody, Yes kinase Antibody, v-yes Antibody, Yes Antibody, Yamaguchi sarcoma oncogene Antibody

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly.

Requested From: 
Date Requested: 5/20/2018

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