Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2F12] (IgG2a,k) to Human YAP / YAP1
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Human YAP / YAP1
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [2F12]
Purified from ascites by Protein A
IHC - Paraffin (5 µg/ml)
Immunofluorescence (10 µg/ml)
Western blot (1 - 5 µg/ml)
Specificity and Use
YAP / YAP1 antibody was raised against yAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Cell lysate) - positive control Hela NE. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Immunofluorescence (30 ug/ml) - positive control HeLa cells. Sandwich ELISA (Recombinant protein).
PBS, pH 7.4.
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
YAP1 Antibody, 65 kDa Yes-associated protein Antibody, YAP Antibody, Yes-associated protein beta Antibody, Yes-associated protein delta Antibody, Yorkie homolog Antibody, YAP2 Antibody, Yes-associated protein 1 Antibody, Yes-associated protein 2 Antibody, YKI Antibody, YAP65 Antibody
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.