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Anti-XRCC5 / Ku80 Antibody (Asp708) LS-C176287

Catalog	Size	Price
LS-C176287-100	100 µl	Unavailable

Related Products

102 XRCC5 / Ku80 Antibodies

Most Popular XRCC5 / Ku80 Antibodies

Anti-XRCC5 / Ku80 Antibody (C-Terminus, clone 149.8) IHC-plus™ LS-B1718

Antibody:	Mouse Monoclonal [clone 149.8] (IgG) to Human XRCC5 / Ku80
Reactivity:	Human
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-XRCC5 / Ku80 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1718 concentration 5 ug/ml.

Anti-XRCC5 / Ku80 Antibody (N-Terminus, clone 9403) IHC-plus™ LS-B1719

Antibody:	Mouse Monoclonal [clone 9403] (IgG) to Human XRCC5 / Ku80
Reactivity:	Human
Application:	IHC, IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-XRCC5 / Ku80 Antibody (aa419-440) LS-C49082

Antibody:	Rabbit Polyclonal to Human XRCC5 / Ku80
Reactivity:	Human, Mouse, Rat, Hamster
Application:	Western blot
Format:	Unconjugated

Detection of Ku80 in either CHO or A549 nuclear extracts (NE) or cytoplasmic lysates (cyto). A Ku80 deficient cell lysate, XRS, was used as a negative control.

Anti-XRCC5 / Ku80 Antibody (clone 5C5) IHC-plus™ LS-B11679

Antibody:	Mouse Monoclonal [clone 5C5] (IgG1) to Human XRCC5 / Ku80
Reactivity:	Human
Application:	IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Format:	Unconjugated

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-XRCC5 / Ku80 Antibody (clone 3241C1a) LS-C342487

Antibody:	Mouse Monoclonal [clone 3241C1a] (IgG1) to Human XRCC5 / Ku80
Reactivity:	Human
Application:	ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, Dot Blot
Format:	Unconjugated

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-XRCC5 mAb.

Antibody:	Rabbit Polyclonal to Human XRCC5 / Ku80
Reactivity:	Human
Application:	IHC, IHC - Paraffin, Immunofluorescence, Western blot
Format:	Unconjugated

IHC of Ku80 (D708) pAb in paraffin-embedded human lung carcinoma tissue.

Western blot of Ku80 (D708) pAb in extracts from COS7 cells.

Details

Target:	Human XRCC5 / Ku80
Host:	Rabbit
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

IHC
IHC - Paraffin
Immunofluorescence
Western blot

Specificity and Use

Immunogen:	XRCC5 / Ku80 antibody was raised against synthetic peptide around Asp708 of human XRCC5 / Ku80
Epitope:	Asp708
Specificity:	Human XRCC5 / Ku80

Packaging

Presentation:	PBS, pH 7.2, 0.05% sodium azide
Storage:	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions:	For research use only.

About XRCC5 / Ku80

Uniprot: P13010 NCBI: NM_021141 NP_066964.1

Synonyms: XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody

Description: Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.

(More About XRCC5 / Ku80)