The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|XRCC2 antibody was raised against synthetic peptide corresponding to the N-terminus of human XRCC2.|
|Immunohistochemistry: 1:200 for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.|
|PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide|
|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.|
|For research use only.|
XRCC2 Antibody, DNA repair protein XRCC2 AntibodyInvolved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks.