Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:1000)
IHC - Frozen (1:1000)
Western blot (1:500 - 1:2000)
Specificity and Use
WFS1 antibody was raised against a 110 amino acid region of the N-terminal region of the human protein.
Detects human, rat and mouse WFS1 protein.
Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry. Western Blot: 1:500-1:2000. Heat samples at 50?C for 30 minutes. Immunoprecipitation: 2ul. Immunofluorescence: 1:200. Immunohistochemistry (Frozen): 1:1000. Immunohistochemistry (paraffin): 1:100.
Supplied as a liquid.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
WFS1 is a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.