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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VTN / Vitronectin Antibody (aa121‑133, clone HV2) LS‑C40236
Antibody
Vitronectin antibody LS-C40236 is an unconjugated mouse monoclonal antibody to human Vitronectin (VTN). Validated for ELISA and WB.
Catalog
Size
Price
LS-C40236-100
100 µl
Unavailable

Popular VTN / Vitronectin Products

Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry
Antibody
Species: Human
Applications: ELISA
Antibody
Species: Human
Applications: ELISA
Antibody
Species: Human
Applications: Western blot, ELISA, Inhibition
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA

Product Description

Vitronectin antibody LS-C40236 is an unconjugated mouse monoclonal antibody to human Vitronectin (VTN). Validated for ELISA and WB.
About VTN / Vitronectin
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. P04004 NM_000638 NP_000629.3

VTN Antibody, Epibolin Antibody, Serum-spreading factor Antibody, VNT Antibody, S-protein Antibody, Somatomedin B Antibody, V75 Antibody, VN Antibody, Complement S-protein Antibody, Serum spreading factor Antibody, Vitronectin Antibody


Specifications

Target
Human VTN / Vitronectin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b,k Monoclonal [HV2]
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • Western blot (1:100)
  • ELISA (1:32000)
Immunogen
Human vitronectin purified from plasma by heparin-affinity chromatography.
Epitope
aa121-133
Specificity
Highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). This antibody is human-specific (no reactivity with cat, dog, cow, sheep, goat, pig, rabbit, horse). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133. Reactivity: Can be used to purify vitronectin from human plasma by affinity chromatography. It can also be used to quantitatively affinity-deplete human plasma or serum of vitronectin. It partially denatures vitronectin upon antibody binding. It binds equally well to native and denatured vitronectin and can be used to quantitative vitronectin in human plasma in a sandwich ELISA with clone 6F211. It does not interfere with the binding of any known vitronectin ligands. Also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well.
Usage
Suitable for use in ELISA, Western Blot. ELISA: 1:32000. Western Blot: 1:100.
Presentation
PBS, pH 7.2, 15 mM sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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