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Anti-VTN / Vitronectin Antibody (aa121-133, clone HV2) LS-C40236

Ordering

Wt. Vol. Conc. Price
- 100 µl - Unavailable

Most Popular VTN / Vitronectin Antibodies

Anti-VTN / Vitronectin Antibody LS-C40241
Mouse Monoclonal (IgG1,k) to Bovine VTN / Vitronectin
Bovine, Sheep
IHC - Frozen, Western blot, ELISA
Unconjugated
Anti-VTN / Vitronectin Antibody LS-C40242
Sheep Polyclonal (IgG) to Human VTN / Vitronectin
Human
ELISA
Unconjugated
Anti-VTN / Vitronectin Antibody (FITC) LS-C150786
Rabbit Polyclonal (IgG) to Human VTN / Vitronectin
Human
ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone HV2] (IgG2b,k) to Human VTN / Vitronectin
Human
Western blot, ELISA
Unconjugated

Details

Human VTN / Vitronectin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal [HV2]
Unconjugated
Protein A/G purified
Unmodified

Applications

  • Western blot (1:100)
  • ELISA (1:32000)

Specificity and Use

VTN / Vitronectin antibody was raised against human vitronectin purified from plasma by heparin-affinity chromatography.
aa121-133
Highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). This antibody is human-specific (no reactivity with cat, dog, cow, sheep, goat, pig, rabbit, horse). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133. Reactivity: Can be used to purify vitronectin from human plasma by affinity chromatography. It can also be used to quantitatively affinity-deplete human plasma or serum of vitronectin. It partially denatures vitronectin upon antibody binding. It binds equally well to native and denatured vitronectin and can be used to quantitative vitronectin in human plasma in a sandwich ELISA with clone 6F211. It does not interfere with the binding of any known vitronectin ligands. Also binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well.
Suitable for use in ELISA, Western Blot. ELISA: 1:32000. Western Blot: 1:100.

Packaging

PBS, pH 7.2, 15 mM sodium azide.
For research use only.

About VTN / Vitronectin

P04004 NM_000638 NP_000629.3

VTN Antibody, Epibolin Antibody, Serum-spreading factor Antibody, VNT Antibody, S-protein Antibody, Somatomedin B Antibody, V75 Antibody, VN Antibody, Complement S-protein Antibody, Serum spreading factor Antibody, Vitronectin Antibody

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Requested From: 
Date Requested: 3/24/2017

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