Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 3H10] (IgG1) to Human VCAM1 / CD106
Human, Monkey, Dog
IHC - Paraffin, Immunofluorescence, Western blot
Mouse Monoclonal (IgG1) to Human VCAM1 / CD106
IHC - Frozen, Western blot, Flow Cytometry, ELISA
Human VCAM1 / CD106
Human (tested or 100% immunogen sequence identity)
IHC - Frozen
Specificity and Use
Recognizes human CD106/VCAM-1.
Flow cytometry. Immunohistochemistry (frozen sections). ELISA. Western blotting. Flow Cytometry: 10 ul/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.1% sodium azide, stabilizing agent.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
Vascular cell adhesion molecule 1, VCAM-1, is a surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of monocytes and lymphocytes. VCAM-1 and integrin alpha-4-beta-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. Studies of heart development have shown that deficiencies of VCAM and in alpha-4 integrin also result in epicardial dissolution and subsequent myocardial thinning.