(tested or 100% immunogen sequence identity)
Vaccinia Virus antibody was raised against live dry smallpox vaccine.
Recognizes the Vaccinia virus, a large poxvirus. Poxviruses are DNA viruses that replicate in the cytoplasm of the host cell and therefore need a large genome to encode for the various proteins involved in DNA replication and transcription. Vaccinia virus infection is very mild and generally causes no symptoms in healthy individuals. Vaccinia infection initiates immune responses that also protects against smallpox, a much more severe disease with a high mortality rate. Vaccinia is best known for its use as a vaccine against smallpox, which was officially declared eradicated in 1980. There is some concern that smallpox might be re-introduced as a biological weapon, as such it might still pose a threat to humanity. Recognizes a 27kD protein in Western blotting of the following viruses: Vaccinia virus strain Elstree, Ectromelia virus strain K-1, Cowpox virus strain Grishak. It might also recognize the same protein in the Smallpox virus.
Western Blot: LS-C58383 detects a band of approximately 27kD under non-reducing conditions.
PBS, pH 7.4, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
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