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Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Does not have ubiquitin-specific peptidase activity, but could be a competitor of ubiquitin C-terminal hydrolases (UCHs).
Gene Name: | ubiquitin specific peptidase 39 |
Family/Subfamily: | Protease , Cysteine C19 |
Synonyms: | USP39, 65K, CGI-21, SAD1, SAD1 homolog, Ubiquitin specific protease 39, SNRNP65, HSPC332 |
Target Sequences: | NM_006590 NP_006581.2 Q53GS9 |
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