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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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USP10 Antibody (aa487‑536) LS‑C145246
USP10 antibody LS-C145246 is an unconjugated rabbit polyclonal antibody to USP10 from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C145246-50
50 µg
Unavailable

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Product Description

USP10 antibody LS-C145246 is an unconjugated rabbit polyclonal antibody to USP10 from human, mouse, rat and other species. Validated for WB.
About USP10
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, BECN1, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Q14694 AL162049 CAB82392.2

USP10 Antibody, KIAA0190 Antibody, Ubiquitin thiolesterase 10 Antibody, UBPO Antibody, Ubiquitin specific protease 10 Antibody, Deubiquitinating enzyme 10 Antibody, Ubiquitin thioesterase 10 Antibody


Specifications

Target
Rat USP10
Host
Rabbit
Reactivity
Rat, Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
USP10 antibody was raised against synthetic peptide located between aa487-536 of rat Usp10 (Q3KR59, NP_001029318). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Xenopus, Stickleback, Zebrafish (100%); Sea squirt (92%).
Blocking Peptide
LS-E21695 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C145246. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa487-536
Specificity
Rat USP10
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
USP10 antibody LS-C145246 Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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