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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UNC45B Antibody (aa235‑264) LS‑C160434
UNC45B antibody LS-C160434 is an unconjugated rabbit polyclonal antibody to UNC45B from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C160434-400
400 µl
Unavailable

Popular UNC45B Products

Western blot of Human 721_B . UNC45B antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Zebrafish
Applications: Western blot
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

UNC45B antibody LS-C160434 is an unconjugated rabbit polyclonal antibody to UNC45B from human and mouse. Validated for IHC and WB.
About UNC45B
UNC45B is a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. Q8IWX7 NP_775259.1

UNC45B Antibody, CMYA4 Antibody, Protein unc-45 homolog B Antibody, Unc-45 homolog B (C. elegans) Antibody, UNC45 Antibody, SMUNC45 Antibody, UNC-45B Antibody, Cardiomyopathy associated 4 Antibody, Striated muscle UNC45 Antibody


Specifications

Target
Human UNC45B
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E2861 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C160434. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa235-264
Specificity
This UNC45B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human UNC45B.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).
UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).

Immunohistochemistry

UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).
UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).

Immunohistochemistry

UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).
UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).

Immunohistochemistry

UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
UNC45B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).
UNC45B Antibody western blot of mouse lung tissue lysates (35 ug/lane). The UNC45B antibody detected the UNC45B protein (arrow).


Requested From: 
Date Requested: 6/21/2018

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