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Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.
Gene Name: | unc-13 homolog B (C. elegans) |
Synonyms: | UNC13B, Munc13-2, Unc-13 homolog B (C. elegans), Unc-13-like (C. elegans), UNC13, Unc13h2, Hmunc13, MUNC13, Protein unc-13 homolog B |
Target Sequences: | NM_006377 NP_006368.3 O14795 |
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