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UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
Gene Name: | UDP glucuronosyltransferase 2 family, polypeptide B15 |
Synonyms: | UGT2B15, UDPGT 2B8, UDPGTh-3, UDPGT2B15, UDP glycosyltransferase 2B15, UDPGTH3, HLUG4, UDPGT 2B15, UGT2B8 |
Target Sequences: | NM_001076 NP_001067.2 P54855 |
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