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Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
Gene Name: | uridine-cytidine kinase 1 |
Synonyms: | UCK1, Cytidine monophosphokinase 1, Uridine-cytidine kinase 1, UCK 1, RP11-334J6.5, URK1, Uridine monophosphokinase 1 |
Target Sequences: | NM_031432 NP_113620.1 Q9HA47 |
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