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Human U2AF1L4 | |
Goat | |
Human (tested or 100% immunogen sequence identity) | |
Polyclonal | |
Unconjugated | |
Immunoaffinity purified | |
Unmodified |
U2AF1L4 antibody was raised against synthetic peptide C-EDGERAVAELSNR from an internal region of human U2AF1L4 (NP_001035515.1 ; NP_659424.2). Percent identity with other species by BLAST analysis: Human (100%), Gibbon (92%), Mouse (85%), Rat (85%), Panda (85%), Dog (85%), Horse (85%), Rabbit (85%), Pig (85%). | ||
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aa82-94 | ||
Human U2AF1L4. This antibody is expected to recognise both reported isoforms (NP_001035515.1 and NP_659424.2). No cross-reactivity with U2AF1 expected. | ||
Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx. 20Da band observed in Human Brain (Cerebellum) and Lung lysates (calculated MW of 21.3kD according to NP_001035515.1). Recommended concentration: 0.1-0.3 ug/ml. |
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide | |
Store at -20°C. Avoid freeze-thaw cycles. | |
For research use only. |
U2AF1L4 Antibody, U2AF1L3V1 Antibody, U2AF1RS3 Antibody, U2 auxiliary factor 26 Antibody, U2AF1-like protein 3 Antibody, U2af26 Antibody, U2AF1-RS3 Antibody, U2AF1L3 Antibody
RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1.
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