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TUBB1 / Tubulin Beta 1 is a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.
Gene Name: | tubulin, beta 1 class VI |
Family/Subfamily: | Tubulin |
Synonyms: | TUBB1, Beta tubulin 1, class VI, Tubulin, beta 1, Class VI beta-tubulin, DJ543J19.4, Tubulin beta-1 chain, Tubulin, beta 1 class VI |
Target Sequences: | NM_030773 NP_110400.1 Q9H4B7 |
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