Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TSTA3 Antibody, 3-5 epimerase/4-reductase Antibody, FX Antibody, GDP-L-fucose synthase Antibody, SDR4E1 Antibody, p35B Antibody, Protein FX Antibody
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
Western blot of GDP-L-fucose synthase Antibody at 2 ug/ml + EC109 whole cell lysate at 20 ug/ml. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size:35 kDa. Observed band size:35 kDa. Additional bands at:27 kDa. We are unsure as to the identity of this extra band. This image was taken for the unconjugated form of this product. Other forms have not been tested.