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Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
Gene Name: | thyroid hormone receptor interactor 4 |
Synonyms: | TRIP4, ASC1, TRIP-4, ASC-1, TR-interacting protein 4, HsT17391 |
Target Sequences: | NM_016213 NP_057297.2 Q15650 |
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