Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2A10-B5] (IgG2a,k) to Human TPSAB1 / Mast Cell Tryptase
IHC - Paraffin, Western blot, ELISA
Human TPSAB1 / Mast Cell Tryptase
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [2A10-B5]
Protein A purified
IHC - Paraffin (1 µg/ml)
Specificity and Use
TPSAB1 / Mast Cell Tryptase antibody was raised against tPSAB1 (AAH28059, 1 a.a. ~ 275 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Cell lysate) - positive control K-562. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections, 1 ug/ml) - positive control human lymph node. Sandwich ELISA (Recombinant protein).
PBS, pH 7.4.
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features.