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May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
Gene Name: | tensin 3 |
Synonyms: | TNS3, H_NH0549I23.2, Tumor endothelial marker 6, TPP, TENS1, TEM6, Tensin 3, Tensin-3 |
Target Sequences: | NM_022748 NP_073585.8 Q68CZ2 |
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