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Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses.
Gene Name: | canopy FGF signaling regulator 3 |
Synonyms: | CNPY3, Canopy 3 homolog (zebrafish), CAG repeat containing, CTG repeat protein 4a, Protein associated with TLR4, Protein canopy homolog 3, TNRC5, CAG4A, CTG4A, ERDA5, PRAT4A |
Target Sequences: | NM_006586 NP_006577.2 Q9BT09 |
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