Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone OX-89] (IgG1) to Mouse TNFSF4 / OX40L
Mouse TNFSF4 / OX40L
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [OX-89]
Specificity and Use
Anti-mouse CD134L (OX40L) monoclonal antibody reacts with a type II membrane protein that is similar to TNF that is found on activated antigen presenting cells (APC's) including B cells, dendritic cells and macrophages. CD134L mRNA is expressed in various.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
TNFSF4 / OX40L is a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.