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Anti-TNFSF10 / TRAIL Antibody (aa95-281, clone 2E5, Azide-free) LS-C45711

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Mouse Monoclonal [clone 2E5] (IgG1) to Human TNFSF10 / TRAIL
Human
Flow Cytometry, Functional Assay
Unconjugated, Azide-free

Details

Human TNFSF10 / TRAIL
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [2E5]
Protein A purified
Azide-free

Applications

Flow Cytometry, Functional Assay
IHC - Paraffin

Specificity and Use

TNFSF10 / TRAIL antibody was raised against recombinant soluble fragment (aa 95-281) of human TRAIL.
aa95-281
Reacts with TRAIL (APO-2L), a 21 kD cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.

Packaging

Azide free PBS, preserved by filter sterilization, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About TNFSF10 / TRAIL

P50591 NM_003810 NP_003801.1

TNFSF10 Antibody, Apo-2L Antibody, APO2L Antibody, Apo-2 ligand Antibody, CD253 Antibody, CD253 antigen Antibody, TRAIL Antibody, Protein TRAIL Antibody, TL2 Antibody

TNFSF10 / TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG.

Requested From: United States
Date Requested: 7/3/2015

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