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Anti-TNFRSF10A / DR4 Antibody LS-C44699

Note: This antibody replaces LS-C57894

Ordering

Wt. Vol. Conc. Price
200 µg - 1 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TNFRSF10A / DR4 Antibodies

Anti-TNFRSF10A / DR4 Antibody IHC-plus™ LS-B604
Rabbit Polyclonal to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (clone 32A1380) IHC-plus™ LS-B2073
Mouse Monoclonal [clone 32A1380] (IgG1) to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot, Flow Cytometry, Neutralization
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (clone HS101) LS-C344759
Mouse Monoclonal [clone HS101] (IgG1) to Human TNFRSF10A / DR4
Human
ICC, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human TNFRSF10A / DR4
Human
Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Human TNFRSF10A / DR4
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • Immunoprecipitation
  • Flow Cytometry (1:50 - 1:100)

Specificity and Use

TNFRSF10A / DR4 antibody was raised against fusion protein containing the extracellular region of CD261 (DR4).
Specific for human death receptor 4 (DR4), also known as CD261 or TRAIL- R1. DR4 is a type I transmembrane protein of 468 amino acids, which is expressed in most human tissues including spleen, peripheral blood leucocytes, thymus and in a variety of tumor-derived cell lines. DR4 plays a role in inducing cell death. The binding of TRAIL to DR4 triggers the activation of pro-caspases 8 and 10, leading to apoptosis.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About TNFRSF10A / DR4

NM_003844

TNFRSF10A Antibody, APO2 Antibody, CD261 Antibody, DR4 Antibody, TRAIL-R1 Antibody, TRAILR-1 Antibody, TRAILR1 Antibody, TRAIL receptor 1 Antibody, CD261 antigen Antibody, Cytotoxic TRAIL receptor Antibody, Death receptor 4 Antibody

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1.

Requested From: United States
Date Requested: 12/5/2016

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