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Anti-TNFRSF10A / DR4 Antibody (clone DR-4-02) LS-C204830

Catalog Size Price
LS-C204830-100 100 µg (1 mg/ml) Unavailable

Most Popular TNFRSF10A / DR4 Antibodies

Anti-TNFRSF10A / DR4 Antibody IHC-plus™ LS-B604
Rabbit Polyclonal to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (Extracellular Domain, clone DJR1) LS-C40989
Mouse Monoclonal [clone DJR1] (IgG1) to Human TNFRSF10A / DR4
Human
Flow Cytometry
Unconjugated
Flow Cytometry Image
Anti-TNFRSF10A / DR4 Antibody (clone 32A1380) IHC-plus™ LS-B2073
Mouse Monoclonal [clone 32A1380] (IgG1) to Human TNFRSF10A / DR4
Human
IHC - Paraffin, Western blot, Flow Cytometry, Neutralization
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10A / DR4 Antibody (clone DR-4-02) LS-C204830
Mouse Monoclonal [clone DR-4-02] (IgG1) to Human TNFRSF10A / DR4
Human
ICC, Immunoprecipitation, Flow Cytometry, Blocking, Functional Assay, Neutralization
Unconjugated
Anti-TNFRSF10A / DR4 Antibody (clone HS101) LS-C344759
Mouse Monoclonal [clone HS101] (IgG1) to Human TNFRSF10A / DR4
Human
ICC, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated

100% Guaranteed
Mouse Monoclonal [clone DR-4-02] (IgG1) to Human TNFRSF10A / DR4
Human
ICC, Immunoprecipitation, Flow Cytometry, Blocking, Functional Assay, Neutralization
Unconjugated

Details

Human TNFRSF10A / DR4
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [DR-4-02]
Unconjugated
Protein A purified
Unmodified

Applications

  • ICC
  • Immunoprecipitation
  • Flow Cytometry
  • Blocking
  • Functional Assay
  • Neutralization

Specificity and Use

TNFRSF10A / DR4 antibody was raised against fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
Monoclonal antibody DR-4-02 recognizes TRAIL-R1 (DR4), a human death receptor 4 (468 amino acids) expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumor-derived cell lines.
Flow Cytometry: Recommended dilution - 3-5 ug/ml. Functional Application: Soluble antibody DR-4-02 blocks apoptosis triggered by a ligand (TRAIL). Plastic-immobilized (cross-linked) DR-4-02 antibody induces apoptosis in sensitive cells. Recommended diluti

Packaging

PBS, pH 7.4, 15 mM sodium azide.
Store at 2-8°C. Do not freeze.
For research use only.

About TNFRSF10A / DR4

NM_003844

TNFRSF10A Antibody, APO2 Antibody, CD261 Antibody, DR4 Antibody, TRAIL-R1 Antibody, TRAILR-1 Antibody, TRAILR1 Antibody, TRAIL receptor 1 Antibody, CD261 antigen Antibody, Cytotoxic TRAIL receptor Antibody, Death receptor 4 Antibody

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1.

Requested From: 
Date Requested: 8/18/2017

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