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Anti-TLR9 Antibody (aa204-224) LS-C187710

Ordering

Wt. Vol. Conc. Price
100 µg - 2 mg/ml $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TLR9 Antibodies

Anti-TLR9 Antibody (Internal) IHC-plus™ LS-B688
Rabbit Polyclonal to Human TLR9
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TLR9 Antibody (C-Terminus) IHC-plus™ LS-B756
Rabbit Polyclonal to Human TLR9
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TLR9 Antibody IHC-plus™ LS-B6184
Rabbit Polyclonal to Human TLR9
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Mouse TLR9
Mouse, Human, Hamster
IHC - Paraffin, Western blot
Unconjugated

Details

Mouse TLR9
Goat
Mouse, Human, Hamster (tested or 100% immunogen sequence identity)
Rat, Dog, Guinea pig, Horse (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Paraffin (1:250)
  • Western blot (1:1000)

Specificity and Use

TLR9 antibody was raised against synthetic peptide LSLKYNNLTKVPRQLPPSLEY-C corresponding to amino acids 204-224 within the N-terminal region of mouse CD289. Percent identity by BLAST analysis: Mouse, Hamster (100%); Rat (95%); Panda, Dog, Cat, Horse, Guinea pig (90%); Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Ferret, Elephant, Pig (86%); Sheep, Goat, Zebu, Bovine, Rabbit (81%).
aa204-224
Recognizes murine Toll-like receptor 9, also known as CD289 or TLR9. CD289 is an 1032 amino acid ~120 kD endosomal single pass type I transmembrane glycoprotein with a number of and a single domain. Recognizes an epitope within the N-terminal (NT) region of CD289, a member of the toll-like receptor family, which triggers MyD88 and TRAF6, resulting in NF-kappaB activation, cytokine secretion and the inflammatory response. CD289 acts as a receptor for unmethylated cytidine-phosphate-guanosine dinucleotides in bacterial DNA (CpG-DNA), playing a primary role in pathogen recognition and activation of innate immunity and has been shown to play a role in defense against systemic mouse cytomegalovirus infection. Is reported as suitable for use in immunocytochemistry on acetone fixed cells.

Packaging

PBS, 0.09% sodium azide, 0.1% BSA
Store at -20°C. Minimize freezing and thawing.
For research use only.

About TLR9

Q9NR96 NM_017442 NP_059138.1

TLR9 Antibody, CD289 Antibody, CD289 antigen Antibody, Scri2a Antibody, Toll-like receptor 9 Antibody

TLR9 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of paraffin-embedded human spleen with Goat anti-mouse CD289

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of paraffin-embedded mouse thymus with Goat anti-mouse CD289

Requested From: United States
Date Requested: 12/3/2016

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