Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TLR7 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
Anti-TLR7 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4828 concentration 10 ug/ml.
Anti-TLR7 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4828 concentration 10 ug/ml.
Western blot of human TLR7 in Ramos cell lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 1 ug/ml.
Intracellular staining by FACS analysis of TLR7 in human PBMCs using LS-B4828 at2 ug/ml. Shaded histogram represents cells alone; green represents rabbit IgG isotype control, ; red represents anti-TLR7 antibody. Goat anti-rabbit PE, was used as secondary.
Requested From: United States
Date Requested: 10/26/2016