Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone MTS510] (IgG2a) to Mouse TLR4/MD-2 Complex
Immunoprecipitation, Flow Cytometry
Mouse TLR4/MD-2 Complex
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MTS510]
Protein G purified
Specificity and Use
In FA, blocks activation of monocytes with LPS (Akashi et al. 2000). This preferentially recognizes TLR4-MD-2 complex than of TLR4 alone. The optimal condition has to be determined for individual experiments.