Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.
Immunohistochemistry-Paraffin: TLR4 Antibody - Analysis of TLR4 in formalin-fixed, paraffin-embedded mouse spleen tissue using TLR4 antibody (A) and mouse isotype control (B) at 5 mg/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TLR4 Antibody - Analysis of TLR4 using antibody at 2 ug/ml on partial recombinant mouse TLR4 protein. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 1/20/2017