Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:16000) & (1 µg/ml)
Specificity and Use
TIRAP antibody was raised against synthetic peptide C-EGEGERDSATVSDL from the C-terminus of human TIRAP (NP_683708.1). Percent identity with other species by BLAST analysis: Human (100%), Gibbon (86%).
LS-E25248 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55600. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human TIRAP. This protein is expected to recognise isoform b (NP_683708.1) only.
TIRAP Antibody, Adapter protein wyatt Antibody, BACTS1 Antibody, Adaptor protein Wyatt Antibody, MyD88 adapter-like protein Antibody, Wyatt Antibody
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system.