Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TIPRL Antibody, Type 2A-interacting protein Antibody, DJ69E11.3 Antibody, RP1-69E11.1 Antibody, TIP Antibody, TIP41 Antibody, TIP41-like protein Antibody
May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-TIPRL mouse monoclonal antibody. (Dilution 1:50).
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-TIPRL mouse monoclonal antibody. (Dilution 1:50).
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIPRL (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIPRL.
Flow cytometric analysis of Jurkat cells, using anti-TIPRL antibody, (Red) compared to a nonspecific negative control antibody (Blue).
Flow cytometric analysis of Hela cells, using anti-TIPRL antibody, (Red) compared to a nonspecific negative control antibody (Blue).
Requested From: United States
Date Requested: 12/10/2016