Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1E8-269] (IgG1) to Human TGFA / TGF Alpha
Human TGFA / TGF Alpha
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1E8-269]
IHC - Paraffin
IHC - Frozen
IHC - Resin
Specificity and Use
TGFA / TGF Alpha antibody was raised against 32-40 AA sequence linked to thyroglobulin.
Recognizes human Protransforming growth factor alpha, cleaved into Transforming growth factor alpha as the mature form and also known as TGF-alpha (TGFalpha), EGF-like TGF or TGF-1> TGFalpha is a 160 amino acid ~17kD mitogenic cytokine.
TGFA / TGF Alpha is a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.