Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen
Western blot (1 µg/ml)
Specificity and Use
TEK / TIE2 antibody was raised against phosphopeptide containing human Tie-2 Y1100 site.
Recognizes human Tie-2 when phosphorylated at Y1102. Species cross-reactivity: Mouse when phosphorylated at Y1100.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1 ug/ml. Immunohistochemistry: 1.7-15 ug/ml. Paraffin-embedded sections of human liver cancer and cryostat sections of mouse embryos.
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose.
500 µl Sterile PBS
Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.
Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis.