Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MEM-262] (IgG2a) to Human TCR Vbeta5
Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Human TCR Vbeta5
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MEM-262]
Protein A purified
Specificity and Use
TCR Vbeta5 antibody was raised against human thymoma cell line HPB-ALL.
Recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies
Western Blotting: Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting. Functional Application: Activates T cells (V beta 5-related subset).
PBS, 15 mM sodium azide, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.