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Anti-TCP1 Antibody (C-Terminus, clone 91a) LS-C63149

Ordering

Wt. Vol. Conc. Price
50 µg - - $295
200 µg - 1 mg/ml $435
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Most Popular TCP1 Antibodies

Anti-TCP1 Antibody (C-Terminus, clone 91a) LS-C63149
Rat Monoclonal [clone 91a] (IgG2a) to Mouse TCP1
Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Drosophila, C. elegans, Plant
Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-TCP1 Antibody (clone 2B2-D6) IHC-plus™ LS-B9358
Mouse Monoclonal [clone 2B2-D6] (IgG1,k) to Human TCP1
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 91a] (IgG2a) to Mouse TCP1
Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Drosophila, C. elegans, Plant
Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Mouse TCP1
Rat
Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Drosophila, C. elegans, Plant (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [91a]
Unconjugated
Protein G purified
Unmodified

Applications

  • Western blot (1:1000)
  • Immunoprecipitation
  • Flow Cytometry (1:100)

  • IHC - Paraffin

Specificity and Use

TCP1 antibody was raised against a purified recombinant mouse TCP-1 construct encoding the C-terminal half of the 1.8 kb full-length Tcp1b gene expressed in E. coli.
C-Terminus
Recognizes an epitope in the C- terminus of mouse TCP-1a (465-AKLRA) and will detect an ~60 kD protein, corresponding to the apparent molecular mass of TCP1 on SDS-PAGE immunoblots, in samples from human, mouse, rat, bovine, canine, guinea pig, hamster, monkey, pig, and rabbit origins, as well as Saccharomyces cerevisiae (weakly, consistent with the epitope sequence being AKLRS), Drosophila, Schizosaccharomyces pombe and C. elegans. In C. elegans CTA-191 reacts with TCP-1a and another CCT subunit (2). In plants, CTA-191 recognizes TCP -1 of Pisum sativum, and the sequence of Arabidopsis thalania TCP-1a over the region of the epitope AKLRA. It has also been shown that CTA-191 reacts with a subunit of a specialized chaperonin which folds phytochrome (3). Cross reactivity with human Hsp60 has been observed with this antibody in immunoblot analysis.

Packaging

PBS, pH 7.2, 0.1 mM PMSF, in 50% glycerol
Store at -20°C.
For research use only.

About TCP1

P17987 NM_030752 NP_110379.2

TCP1 Antibody, CCTA Antibody, CCT-alpha Antibody, D6S230E Antibody, T-complex 1 Antibody, TCP-1-alpha Antibody, Tailless complex polypeptide 1 Antibody, CCT1 Antibody

TCP1 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.

Requested From: United States
Date Requested: 12/7/2016

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