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TCF12 / HEB is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene Name: | transcription factor 12 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | TCF12, BHLHb20, E-box-binding protein, HEB, HsT17266, HTF4, TCF-12, Transcription factor 12, Transcription factor HTF-4, DNA-binding protein HTF4 |
Target Sequences: | NM_003205 NP_003196.1 Q99081 |
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