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Plays a role in the negative regulation of NF-kappa-B signaling at the basal level by modulating transcriptional activity of NF-kappa-B on its target gene promoters. Associates with cyclin D1 promoter containing Myc E-box sequence and transcriptionally represses cyclin D1 expression. Regulates telomerase reverse transcriptase expression and telomerase activity in both ALT (alternative lengthening of telomeres)and telomerase-positive cell lines.
Gene Name: | transcription elongation factor A (SII)-like 7 |
Synonyms: | TCEAL7, MPMGp800C04260Q003, TCEA-like protein 7 |
Target Sequences: | NP_001120641.1 |
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