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TBX22 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | T-box 22 |
Synonyms: | TBX22, CLPA, DJ795G23.1, CPX, TBXX, T-box 22, T-box protein 22, TBOX22 |
Target Sequences: | NM_016954 NP_058650.1 Q9Y458 |
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