Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone G8.8] (IgG2a) to Mouse TACSTD1 / EPCAM
IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Mouse TACSTD1 / EPCAM
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [G8.8]
IHC - Frozen (1:25 - 1:200)
Western blot (1:100 - 1:1000)
Flow Cytometry (1:25 - 1:200)
IHC - Paraffin
Specificity and Use
TACSTD1 / EPCAM antibody was raised against glycoconjugates isloted from TE-71 BALB/c mouse derived medullary thymic epithelial cells and rat X63-Ag8.653 myeloma cells
reacts with CD326/Ep-CAM (Epithelial Cell Adhesion Molecule), also known as gp-40 in the mouse. Ep-CAM is a 40-42-kDa cell-surface glycoprotein expressed on thymic epithelial cells, thymic dendritic cells, immature thymocytes, a small subset of peripheral T lymphocytes, intestinal epithelium, kidney-collecting tubule epithelium, keratinocytes, Langerhans cells, as well as lymph node and splenic dendrititc cells.
PBS containing 0.09% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.