Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human TAC1 / Substance P
IHC - Paraffin, IHC - Frozen
Human TAC1 / Substance P
Human, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen
Specificity and Use
Synthetic Substance P 4-11, conjugated to thyroglobulin using CDI.
Recognizes Substance P. Absorption with 10-100 ug SP 1-4 per ml diluted antiserum abolishes the staining. Species cross-reactivity: Human and rat.
Suitable for use in Immunohistochemistry (frozen and paraffin-embedded tissue, no proteolytic treatment required). Immunohistochemistry: 1:400-1:800 using PAP, with overnight incubation at 2-8?C. Positive control: Frozen sections of rat colon.
TAC1 / Substance P is four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties.