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Anti-SYN / FYN Antibody (aa1-30) LS-C166293

Catalog	Size	Price
LS-C166293-400	400 µl	Unavailable

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Anti-SYN / FYN Antibody (phospho-Tyr213) LS-C291503

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Anti-SYN / FYN Antibody (N-Terminus) LS-C330447

Antibody:	Rabbit Polyclonal (IgG) to Human SYN / FYN
Reactivity:	Human, Mouse
Application:	IHC, Western blot, ELISA
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human SYN / FYN
Reactivity:	Human
Application:	IHC - Paraffin, Western blot, Flow Cytometry
Format:	Unconjugated

Details

Target:	Human SYN / FYN
Host:	Rabbit
Reactivity:	Human (tested or 100% immunogen sequence identity)
Predicted:	Pig, Cow (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated
Purification:	Protein A purified
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (1:50 - 1:100)
Western blot (1:1000)
Flow Cytometry (1:10 - 1:50)

Specificity and Use

Blocking Peptide:

LS-E9211 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C166293. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa1-30

Specificity:

This FYN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FYN.

Packaging

Presentation:	PBS, 0.09% sodium azide
Storage:	Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions:	For research use only.

About SYN / FYN

Uniprot: P06241 NCBI: NM_002037 NP_002028.1

Synonyms: FYN Antibody, C-syn protooncogene Antibody, Fyn kinase Antibody, Fyn tyrosine kinase Antibody, p59-FYN Antibody, SYN Antibody, Src-like kinase Antibody, Src/yes-related novel Antibody, Tyrosine kinase fyn Antibody, Tyrosine kinase p59fyn(T) Antibody, Tyrosine-protein kinase Fyn Antibody, Proto-oncogene c-Fyn Antibody, Proto-oncogene Syn Antibody

Description: Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.

(More About SYN / FYN)

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Technical Help Review

Review This Product

Immunohistochemistry

Formalin-fixed and paraffin-embedded human brain tissue reacted with FYN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

Western blot of FYN Antibody in HeLa cell line lysates (35 ug/lane). FYN (arrow) was detected using the purified antibody.

Flow Cytometry

FYN Antibody flow cytometry of HeLa cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From:
Date Requested: 8/21/2017

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