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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SRSF2 / SC35 Antibody (aa46‑57) LS‑C10325
SC35 antibody LS-C10325 is an unconjugated rabbit polyclonal antibody to SC35 (SRSF2) from human, mouse, rat and other species. Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C10325-50
50 µg
$345
LS-C10325-100
100 µg
$465

Popular SRSF2 / SC35 Products

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SFRS2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-SRSF2 / SC35 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9760 concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Chicken, Xenopus
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: Western blot
Western blot of SRSF2 / SC35 antibody.
Species: Human
Applications: IHC, Western blot

Product Description

SC35 antibody LS-C10325 is an unconjugated rabbit polyclonal antibody to SC35 (SRSF2) from human, mouse, rat and other species. Validated for ELISA.
About SRSF2 / SC35
Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Q01130 NM_003016 NP_003007.2

SRSF2 Antibody, PR264 Antibody, Protein PR264 Antibody, SFRS2 Antibody, Splicing component, 35 kDa Antibody, Splicing factor sc35 Antibody, SR splicing factor 2 Antibody, SRp30b Antibody, SC35 Antibody, SC-35 Antibody, SFRS2A Antibody


Specifications

Target
Human SRSF2 / SC35
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Pig, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Drosophila (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ELISA (1:112000)
Immunogen
SRSF2 / SC35 antibody was raised against synthetic peptide corresponding to aa46-57 [PRDRYTKESRGF] Coupled with KLH. MW of Antigen: 25.47kD. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Seabass, Salmon, Stickleback, Zebrafish (100%); Medaka, Drosophila (92%); Rabbit, Seq squirt, Mosquito, Sea anemone, Ant, Nematode, Beetle (83%).
Epitope
aa46-57
Specificity
Recognizes human Splicing Factor, Arginine/Serine-Rich 2.
Usage
Suitable for use in ELISA. ELISA: 1:112000 (Serum Titer).
Presentation
PBS, pH 7.2, 0.1% Sodium Azide, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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