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Anti-SRSF1 / SF2 Antibody (N-Terminus) IHC-plus™ LS-B2340

Note: This antibody replaces LS-C17896


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular SRSF1 / SF2 Antibodies

Anti-SRSF1 / SF2 Antibody (N-Terminus) IHC-plus™ LS-B2340
Mouse Monoclonal (IgG2b) to Human SRSF1 / SF2
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry Image
Anti-SRSF1 / SF2 Antibody (aa158-186) LS-C169019
Rabbit Polyclonal to Human SRSF1 / SF2
IHC - Paraffin, Western blot, Flow Cytometry
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2b) to Human SRSF1 / SF2
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation


Human SRSF1 / SF2
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Protein A purified


  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence
  • Western blot (0.5 - 1 µg/ml)
  • Immunoprecipitation

Specificity and Use

SRSF1 / SF2 antibody was raised against recombinant SF2/ASF protein.
Recognizes the N-terminal portion (aa1-97) of the SF2/ASF protein comprising the RNA-recognition motif (RRM1). Reactivity is not affected by phosphorylation state of SF2/ASF. Species cross-reactivity: Human (HeLa cells), mouse and rat. Cross-reactivity expected with other species because SF2/ASF is highly conserved.
Immunohistochemistry: LS-B2340 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2340 was determined to be 5 ug/ml.


PBS, pH 7.4, 0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SRSF1 / SF2

Q07955 NM_006924 NP_008855.1

SRSF1 Antibody, Alternative-splicing factor 1 Antibody, ASF Antibody, SF2 Antibody, SF2p33 Antibody, SFRS1 Antibody, Splicing factor 2 Antibody, ASF-1 Antibody, SR splicing factor 1 Antibody, SRp30a Antibody

Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.


Anti-SF2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2340 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/23/2016

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